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HEPATOCELLULAR CARCINOMA (HCC)
Measures:
Lab Studies:
Tumor Markers:
Imaging Studies:
Radiation Therapy:
Liver Biopsy:
Informed Consent for Image-guided
Procedures:
Testing for the underlying cause of HCC:
Tests for Alcoholism:
Tests for viral hepatitis:
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Test for HBsAg - American Association
for Clinical Chemistry
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http://www.labtestsonline.org/understanding/analytes/hepatitis_b/test.html
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US
National Centre for Infectious Diseases: Interpretation of the Hepatitis B Panel
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http://www.cdc.gov/ncidod/diseases/hepatitis/b/Bserology.htm
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Special Considerations in Interpreting Liver
Function Tests: A
number of pitfalls can be encountered in the interpretation of common blood
liver function tests. These tests can be normal in patients with chronic
hepatitis or cirrhosis. The normal range for aminotransferase levels is slightly
higher in males, nonwhites and obese persons. Severe alcoholic hepatitis is
sometimes confused with cholecystitis or cholangitis. Conversely, patients who
present soon after passing common bile duct stones can be misdiagnosed with
acute hepatitis because aminotransferase levels often rise immediately, but
alkaline phosphatase and gamma-glutamyltransferase levels do not become elevated
for several days. Asymptomatic patients with isolated, mild elevation of either
the unconjugated bilirubin or the gamma-glutamyltransferase value usually do not
have liver disease and generally do not require extensive evaluation. Overall
hepatic function can be assessed by applying the values for albumin, bilirubin
and prothrombin time in the modified Child-Turcotte grading system -
http://www.aafp.org/afp/990415ap/2223.html
- Guidelines for
Laboratory Testing and Result Reporting of Antibody to Hepatitis C Virus:
Testing for the presence of antibody to hepatitis C virus (anti-HCV) is
recommended for initially identifying persons with hepatitis C virus (HCV)
infection. Substantial variation in reflex supplemental testing practices exists
among laboratories, and an anti-HCV–positive laboratory report does not
uniformly represent a confirmed positive result. These guidelines expand
recommendations for anti-HCV testing to include an option for reflex
supplemental testing based on screening-test– positive signal-to-cut–off (s/co)
ratios. Use of s/co ratios minimizes the amount of supplemental testing that
needs to be performed while improving the reliability of reported test results.
Adoption of these guidelines by all public and private laboratories that perform
in vitro diagnostic anti-HCV testing will improve the accuracy and utility of
reported anti-HCV test results for counseling and medical evaluation of patients
by health-care professionals and for surveillance by public health departments -
http://www.cdc.gov/mmwr/PDF/rr/rr5203.pdf
Tests for
Hemochromatosis:
Statistics:
Screening For HCC:
Document Author: Dr. Fazal Danish
Document Created: 30th March 2006
Document Edits:
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