MALARIA

Overviews:

• U.S. Department of Health and Human Services: Malaria Review (besides malaria disease review, also includes information on mosquito, drugs and vaccine research) - http://www.niaid.nih.gov/publications/malaria/pdf/malaria.pdf

• Malaria: a comprehensive review - http://www.emedicine.com/Med/topic1385.htm
• Medline Plus: Malaria overview - http://www.nlm.nih.gov/medlineplus/ency/article/000621.htm
• Life cycle of Plasmodium - http://www.dpd.cdc.gov/dpdx/HTML/Malaria.asp?body=Frames/M-R/Malaria/body_Malariadiagfind1.htm
• CDC: Frequently Asked Questions about Malaria - http://www.cdc.gov/malaria/faq.htm
• WHO: Guidelines for the Treatment of Malaria - http://www.who.int/malaria/docs/TreatmentGuidelines2006.pdf
• Special Programme for Research and Training in Tropical Diseases (TDR): Malaria Review - http://www.who.int/tdr/diseases/malaria/default.htm

Malaria in Pregnancy:

• WHO: Lives at risk: malaria in pregnancy - http://www.who.int/features/2003/04b/en/

Geographical Distribution of malaria:

• Geographical Distribution of malaria - http://www.dpd.cdc.gov/dpdx/HTML/Malaria.asp?body=Frames/M-R/Malaria/body_Malariadiagfind1.htm

Measures:

Overviews of diagnostic tests:

• WHO: The Use of Malaria Rapid Diagnostic Test (RDT) - http://www.wpro.who.int/NR/rdonlyres/0DED6EE5-AE1E-4907-A45A-B3041E6D88CA/86/file_Malaria_Rapid_Diagnostic_Tests.pdf

• CDC (Centre for disease control and prevention): Diagnosis of Malaria - http://www.cdc.gov/malaria/diagnosis_treatment/diagnosis.htm

Microscopic Tests (Peripheral Smear Study + Quantitative Buffy Coat (QBC) Test):

• American Association of Clinical Chemistry: Peripheral blood smear (also called red blood cell morphology) - http://www.labtestsonline.org/understanding/analytes/blood_smear/glance.html
• Thick and Thin blood films and microscopy - http://www.dpd.cdc.gov/dpdx/HTML/Malaria.asp?body=Frames/M-R/Malaria/body_Malariadiagfind1.htm

• Comparison of the Plasmodium Species which cause Human Malaria - http://www.dpd.cdc.gov/dpdx/HTML/PDF_Files/Malaria%20Comparison%20p1-2.pdf

• Thick Blood Smears of different Plasmodium Species - http://www.dpd.cdc.gov/dpdx/HTML/PDF_Files/Malaria%20Comparison%20p7-8.pdf

• Thin Blood Smears of different Plasmodium Species - http://www.dpd.cdc.gov/dpdx/HTML/PDF_Files/Malaria%20Comparison%20p3-6.pdf

• Quantitative Buffy Coat (QBC) Test - http://www.malariasite.com/malaria/QBC.htm

Rapid Diagnostic Tests ( RDTs):

• Rapid Diagnostic Tests - RDTs (Para Sight F test + OptiMal Assay + The immuno chromatographic test (ICT Malaria P. f. test)) - http://www.malariasite.com/malaria/rdts.htm

Other tests that may be the part of diagnostic work-up:

• PCR, Serology, Intraleucocytic malaria pigment, Flowcytometry, Mass spectrometry - http://www.malariasite.com/malaria/other_tests.htm#PCR

• Species-specific PCR diagnosis of malaria - http://www.dpd.cdc.gov/dpdx/HTML/Malaria.asp?body=Frames/M-R/Malaria/body_Malariadiagfind1.htm

• Serology: Indirect Fluorescent Antibody (IFA) Test for Plasmodium - http://www.dpd.cdc.gov/dpdx/HTML/Malaria.asp?body=Frames/M-R/Malaria/body_Malariadiagfind1.htm

• American Association of Clinical Chemistry: Blood Culture - http://www.labtestsonline.org/understanding/analytes/blood_culture/glance.html

• American Association of Clinical Chemistry: Fasting blood sugar (FBS) - http://www.labtestsonline.org/understanding/analytes/glucose/glance.html

• American Association of Clinical Chemistry: Haemoglobin (Hb) - http://www.labtestsonline.org/understanding/analytes/hemoglobin/glance.html

• American Association of Clinical Chemistry: Platelet Count - http://www.labtestsonline.org/understanding/analytes/platelet/glance.html

• American Association of Clinical Chemistry: Liver (Hepatic) Function Tests - http://www.labtestsonline.org/understanding/analytes/liver_panel/glance.html

• American Association of Clinical Chemistry: Glucose-6-Phosphate Dehydrogenase (G-6-PD) - http://www.labtestsonline.org/understanding/analytes/g6pd/glance.html

• American Association of Clinical Chemistry: Blood Urea Nitrogen (BUN) - http://www.labtestsonline.org/understanding/analytes/bun/glance.html

• American Association of Clinical Chemistry: Creatinine - http://www.labtestsonline.org/understanding/analytes/creatinine/glance.html

• American Association of Clinical Chemistry: Urinalysis - http://www.labtestsonline.org/understanding/analytes/urinalysis/glance.html

• The Royal College of Pathologists of Australasia (RCPA): Widal Test (Serum Typhoid antibodies) - http://www.rcpamanual.edu.au/sections/pathologytest.asp?s=33&i=171

• The Royal College of Pathologists of Australasia (RCPA): Cerebrospinal fluid examination - http://www.rcpamanual.edu.au/sections/pathologytest.asp?s=33&i=181

Malaria Research:

• US National Institute of Allergy and Infectious Diseases (NIAID): Malaria Research Fact Sheet - http://www.niaid.nih.gov/factsheets/Malaria2.htm

• Malaria Research and Reference Reagent Resource Center - http://www.malaria.mr4.org/

• CDC: Malaria Research - http://www.cdc.gov/malaria/cdcactivities/research.htm

Malaria Genome:

• NCBI: Malaria Genetics and Genomics - http://www.ncbi.nlm.nih.gov/projects/Malaria/

• The Plasmodium Genome Resource - http://plasmodb.org/

• TIGR: The Plasmodium Falciparum Genome Database (PFDB) - http://www.tigr.org/tdb/edb2/pfa1/htmls/

• Malarial Parasite Metabolic Pathways - http://sites.huji.ac.il/malaria/

• University of Florida: Malaria Genome Tag Sequencing Project - http://parasite.vetmed.ufl.edu/

Malaria Epidemiology:

• Malaria Epidemiology - http://www.malaria.org/epidemiology.html

Malaria Control & Prevention:

• WHO: Malaria control in complex emergencies: An Inter-Agency Field Handbook - http://www.who.int/malaria/docs/ce_interagencyfhbook.pdf

• WHO: Global Strategic Plan 'Roll Back Malaria' 2005-2015 - http://www.rollbackmalaria.org/forumV/docs/gsp_en.pdf

• Mayo Clinic: Keep mosquitoes at bay - http://www.mayoclinic.com/health/insect-repellent/FL00083

• US Environmental Protection Agency: Methods of Mosquito Control - http://www.epa.gov/pesticides/health/mosquitoes/mosquito.htm

• CDC: Malaria and Travellers - http://www.cdc.gov/malaria/travel/index.htm

• CDC: Regional Malaria Information for Travellers - http://www.cdc.gov/travel/regionalmalaria/

• CDC: Preventing Malaria in Infants and Children: Information for the Public - http://www.cdc.gov/travel/mal_kids_pub.htm

• CDC: Preventing Malaria in the Pregnant Woman: information for the Public - http://www.cdc.gov/travel/mal_preg_pub.htm

Statistics:

• WHO: World Malaria Report 2005 - http://rbm.who.int/wmr2005/index.html

• WHO: World Malaria Report 2005: Global Malaria Situation - http://rbm.who.int/wmr2005/html/1-1.htm

• Malaria Case Burden: Country-wise data (provided only for those countries in which malaria is considered to be endemic) - http://www.globalhealthfacts.org/topic.jsp?i=20

• Malaria Case Rate per 1,000 Population: Country-wise data (provided only for those countries in which malaria is considered to be endemic) - http://www.globalhealthfacts.org/topic.jsp?i=21

• Malaria Deaths: Country-wise data (provided only for those countries in which malaria is considered to be endemic) - http://www.globalhealthfacts.org/topic.jsp?i=22

Malaria Strategy:

• Republic of Kenya: Ministry of Health: National Malaria Strategy 2001-2010: an introduction - http://www.kmis.org/Publications/National%20Malaria%20Strategy/Short%20version.pdf

• Republic of Kenya: Ministry of Health: National Malaria Strategy 2001-2010: the detailed version - http://www.kmis.org/Publications/National%20Malaria%20Strategy/Long%20version.pdf

Document Provenance and History

Document Author: Dr. Fazal Danish

Document Created: 25th April 2006

Document Edits: