If you publish work using results from CubeX,
please cite our 2007
BMC Bioinformatics paper
Please enter valid positive integers in all 9 cells.
This program calculates haplotype
frequencies using the exact
solution to the cubic equation rather than an iterative approach.
Please enter the observed diplotype numbers in the cells of the table
above, then click submit to analyse. Values should be positive integers.
CubeX for batch use
to download a version of
CubeX (Python script) for batch use. This takes diplotype inputs from
file (one SNP pair per line) and exports xml.
Update: 12 April 2012 fixed bug which caused some inputs to fail with a string/list concatenation error.
Copyright and Licence
This program is copyright (2006-7). Use is
free under the terms of the CubeX
licence, but no liability is accepted for any costs or errors
use of the software. Any use of the program should be cited in
exact solutions for
the estimation of pairwise haplotype frequencies: implications for
linkage disequilibrium analyses and a web tool 'CubeX'
Tom R Gaunt, Santiago Rodriguez, Ian NM Day
Bioinformatics 2007, 8:428 (2 November 2007)
Any user wishing to obtain the code for
their own use should contact