Case & Family Studies

(country then alphabetical order)

Countries:

  • Australia
  • Denmark
  • EIRE
  • Finland
  • Germany
  • Holland
  • Italy
  • International
  • Japan
  • New Zealand
  • Philippines
  • Sweden
  • United Kingdom
  • United States of America

Australia

  • Australian and New Zealand Clinical Trials Registry (ANZCTR): “The ANZCTR will include information about: clinical trials into pharmaceuticals, surgical procedures, preventive measures, lifestyle, devices, rehabilitation strategies and complementary therapies; and all clinical trials involving Australian researchers and participants and covering all areas of health. Case selections based on genetic criteria, and other genetic studies are now relevant to numerous trials.” – http://www.actr.org.au/actr/handler?Action=home
  • Hunter DNA Bank for Schizophrenia and Allied Disorders: “The DNA Bank has been established in the first instance in the Hunter region, where sufficiently large samples of people with schizophrenia and their families are located. Volunteers with schizophrenia, their first-degree relatives and people without a personal or family history of mental illness will be recruited through the resources of the NISAD Schizophrenia Research Register. The facilities of the Medical Genetics laboratory, situated at the John Hunter Hospital in Newcastle, will be used to process the blood samples. Genomic DNA, RNA and lymphocytes will be isolated and stored. The samples will then be made available for research projects investigating the genetics of schizophrenia. Researchers wishing to use these samples would be required to apply to the DNA Bank for Schizophrenia Research for permission, giving details of the proposed project.” – http://www.newcastle.edu.au/centre/cmhs/projects/nisadd.html

Denmark

  • Danish Twin Registry: “The Danish Twin Registry (DTR) is one of the oldest twin registries in the world. It was established in the 1950’es with the aim of studying causes of cancer, and through the years it has gradually been expanded so that it now comprises twins born through more than 130 years.” – http://www.dtr.sdu.dk/?sideid=index&sprog=eng

EIRE

  • Pharmacogenetics of Vascular Disease – RCSI, Dublin, Eire: “bioresources at SurGen: hypertension and metabolic syndrome phenotypes on 1,400 normal subjects, 125 BPU hypertensives, 260 SPP100-04 hypertensives; ASCOT 6yeay follow-up on 9,500 hypertensives; ASCOT HACVD detailed cv risk data on 1,000 hypertensives. ADVANCE (with Sydney, Australia) 10,000 diabetics 5 year follow-up. 2,000 pateints with regular retinal photography. 400 patients with regular oxidative stress measurements.” – http://www.inst-biopharmsci.org/subhtml/projects_stanton.htm

Finland

  • Botnia Study (type 2 diabetes): “The Botnia Study was begun in 1990 in Pohjanmaa, Finland. From five public health care districts (Malax, Korsholm, Närpes, Jakobstad, Vasa) all the people suffering from adult-onset (type 2) diabetes and their families were invited to participate in the study. In 1994 the study was expanded to the rest of Finland and to the south of Sweden (so called SIB-study). Altogether more than 9000 persons from 1400 families have participated in the study. During the last few years the study has expanded to people with young-onset (type 1) diabetes.” – http://www.botnia-study.org/e/index.html

Germany

  • Baden-Württemberg consortium on Addiction: “The DNA bank “Addiction” collects blood and extracts DNA of the samples recruited by the Baden-Württemberg consortium on addiction research. Furthermore, genotyping and association analyses of functionally related candidate genes of neurosignalling pathways relevant to addiction are being performed.” – http://www.zi-mannheim.de/808.html

Holland

  • Dutch Twin Registry: “Het Nederlands Tweelingen Register (kortweg NTR) werd op 1 februari 1987 aan de Vrije Universiteit te Amsterdam opgericht ten behoeve van wetenschappelijk onderzoek. Onderzoek bij tweelingen en hun familieleden kan namelijk inzicht verschaffen in de mate waarin verschillen tussen mensen bepaald worden door erfelijke of omgevingsinvloeden. Door de continue hulp van de tweelingen en hun families die bij het NTR staan ingeschreven onderzoekt het NTR de invloed van genen en omgeving op onder andere de ontwikkeling van de hersenen, intelligentie, probleemgedrag van kinderen, gezondheid en leefgewoonten, angst en depressie, persoonlijkheid en veroudering.” – http://www.tweelingenregister.org/

Italy

  • GENIPER Project: “The GENIPER database is the result of a collaborative effort of 13 Italian research centres to collect genomic DNA in subjects well characterized in terms of blood pressure status. The GENIPER DNA bank consists of approximately 3200 DNA samples, obtained from members of hypertensive families, individual hypertensive cases and” – http://www.jhypertension.com/pt/re/jhypertension/abstract.00004872-200310000-00012.htm
  • Italian Twin Registry: “Responsabile: Antonia Stazi, epidemiologa. stazi@iss.it” – http://www.gemelli.iss.it/

International

  • European Type 1 Diabetes Genetics Network: “The ET1DGN is part of the international effort of the Type 1 Diabetes Genetics Consortium (T1DGC) to identify and collect families in which at least 2 siblings suffer from type 1 diabetes, in order to search for genetic markers of the disease. The project is carried out in collaboration with other regional networks (Latin-America, Asia Pacific, North America and United Kingdom) and is funded by the NIH. The aim of the ET1DGN is to recruit at least 1200 families in the European region, representing as diversified a population as possible in order to secure a broad scientific base. To achieve its goals, the ET1DGN seeks to establish, maintain and promote a network of collaborating centers in as many European countries as possible” – http://et1dgn.org/
  • GenomEUtwin: “The participating 8 twin cohorts form a collection of over 0.6 million pairs of twins. Tens of thousands of DNA samples with informed consents for genetic studies of common diseases have already been stored from these population-based twin cohorts. The population cohorts used in the Genomeutwin study consist of Danish, Finnish, Italian, Dutch and Swedish twins and the MORGAM population cohort.” – http://www.genomeutwin.org/index.htm
  • International Multi-center ADHD Genetics Project (IMAGE): “The Neuropsychiatric Genetics group at TCD have been funded by the US National Institute of Mental Health over a five year period to take part in the IMAGE programme on the Genetics of ADHD. This major international project is a collaboration between Trinity College, the Institute of Psychiatry in London, the Harvard Medical School/Massachusetts General Hospital and clinical centres throughout Europe. More information at http://www.tcd.ie/Psychiatry/Neuropsychiatry/IMAGE.pdf” – http://www.tcd.ie/Psychiatry/Neuropsychiatry/image.htm
  • International Myeloma Foundation DNA Bank: “More than 3,000 DNA samples have been collected so far from myeloma patients in groups that have been treated with conventional medications, high dose therapies or with the novel medications. The samples along with the custom gene chip analyzers and other high tech equipment are housed at the University of Minnesota under the direction of Dr. Van Ness, and at the Institute of Cancer Research in London under the direction of Dr. Morgan. The International Myeloma Foundation expects the number of samples collected to double in the next two years” – http://www.myeloma.org/main.jsp?type=article&id=1660
  • MIRAGE (Multi Institutional Research of Alzheimer Genetic Epidemiology) Project: “The MIRAGE (Multi Institutional Research of Alzheimer Genetic Epidemiology) Project, funded by the National Institute on Aging since 1991, is the largest genetic epidemiology study of AD in the world. 12 center study of gene-environment interaction between USA, Canada and Germany.” –  http://genetics.bumc.bu.edu/research/alzres.htm
  • Type 1 Diabetes Genetics Consortium (T1DGC): “The international Type 1 Diabetes Genetics Consortium (T1DGC) is a collaborative group formed to facilitate the genetic analysis of Type 1 diabetes (T1D) via the sharing of reagents, methods, strategies, samples, knowledge and data at all levels. There are extensive ongoing further colelctions, linkage and whole genome association scans for thousands of affected sib pairs and nuclear families. Consortium agreement at http://www.t1dgc.org/docs/T1DGC_Consortium_Agreement.pdf” – http://www.t1dgc.org/
  • WHO International Clinical Trials Registry Platform (ICTRP): “World Health Organisation portal for Clinical Trials. Numerous therapeutic trials now have genetic selection criteria or use genetic studies as part of design or follow up.” – http://www.who.int/ictrp/en/

Japan

  • JSSLG – Japanese Schizophrenia Sib-Pair Linkage Group: “The Japanese Schizophrenia Sib-Pair Linkage Group (JSSLG) is a multisite collaborative study group that was organized to create a national resource for affected sib pair (ASP) studies of schizophrenia in Japan. We used a high-density single-nucleotidepolymorphism (SNP) genotyping assay, the Illumina BeadArray linkage mapping panel (version 4) comprising 5,861 SNPs, to perform a genomewide linkage analysis of JSSLG samples comprising 236 Japanese families with 268 nonindependent ASPs with schizophrenia. All subjects were Japanese.” – http://www.journals.uchicago.edu/cgi-bin/resolve?id=doi:10.1086/498122

New Zealand

  • Australian and New Zealand Clinical Trials Registry (ANZCTR): “The ANZCTR will include information about: clinical trials into pharmaceuticals, surgical procedures, preventive measures, lifestyle, devices, rehabilitation strategies and complementary therapies; and all clinical trials involving Australian researchers and participants and covering all areas of health. Case selections based on genetic criteria, and other genetic studies are now relevant to numerous trials.” – http://www.actr.org.au/actr/handler?Action=home

Philippines

  • Clefts of the lip and palate “are common human birth defects of multifactorial etiology and with important surgical, medical, speech, behavioral and developmental implications. Currently, we are carrying out an expanded case ascertainment using both surveillance systems in the United States and overseas, particularly in the Philippines under the auspices of Operation Smile.” http://genetics.uiowa.edu/projects/projectDescriptions/MolEpiCLP.htm

Sweden

  • Botnia Study (type 2 diabetes): “The Botnia Study was begun in 1990 in Pohjanmaa, Finland. From five public health care districts (Malax, Korsholm, Närpes, Jakobstad, Vasa) all the people suffering from adult-onset (type 2) diabetes and their families were invited to participate in the study. In 1994 the study was expanded to the rest of Finland and to the south of Sweden (so called SIB-study). Altogether more than 9000 persons from 1400 families have participated in the study. During the last few years the study has expanded to people with young-onset (type 1) diabetes.” – http://www.botnia-study.org/e/index.html
  • The Swedish Twin Registry “is the largest twin register in the world and includes more than 140,000 twins. The registry covers three different age cohorts, the older cohort, the middle cohort, and the younger cohort. The purpose of twin studies is to study the relative importance of genetic and environmental influences for behavioral characteristics and diseases. There are about 30 ongoing research projects using data from the Swedish Twin Registry.” – http://www.meb.ki.se/twinreg/index_en.html

United Kingdom

  • The British Genetics of Hypertension (BRIGHT) study – “…a research collaboration between 6 UK universities with the aim of finding genes causing high blood pressure using large-scale family studies. We hope that the discovery of genes causing high blood pressure will ultimately lead to new diagnostics, improved therapeutic targets and better prediction of those at greatest risk”. http://www.brightstudy.ac.uk/
  • Catalogue of MRC funded UK DNA Banking Network Case studies: “In 2000 the draft sequence of the human genome was published and the UK MRC identified genetic epidemiology as a strategically important area for translating knowledge of the human genome sequence into real benefits for human health. MRC made awards that year to enable collection of large numbers of samples in 13 common diseases of major public health impact. For further details on each study see the catalogue. These samples were to be managed centrally as national resources and be made widely available.” – http://www.dna-network.ac.uk/Studies/
  • Current Controlled Trials (UK): “Current Controlled Trials allows users to search, register and share information about randomised controlled trials. Access to all the information on this site is free; charges for the registration services offered by Current Controlled Trials are available on request. Case selection based on genetic criteria and genetic studies in general, are now relevant to numerous trials.” – http://www.controlled-trials.com/
  • Glomurulonephritis national DNA bank: “DNA from over 2,500 probands and controls has been banked. The bank is probably the largest collection of DNA from patients with glomerular disease in the world but is still being expanded.The objective was to collect and archive DNA together with EBV transformed cell lines, serum and clinical data from a sufficiently large cohort of patients to enable suitably empowered genetic studies to be performed on five of the most common types of glomerulonephritis: – IgA nephropathy, membranous nephropathy, focal necrotising glomerulonephritis (FNGN), lupus nephropathy and minimal change nephritic syndrome.” – http://www.renal.org/Research/GN-DNAbank.html
  • Insitute of Cancer Research UK collections “(numerous cancer types) Non-medullary thyroid cancer (NMTC) Chronic Lymphocytic Leukaemia (CLL)[International Consortium to collect multiple case families]Collaborative venture between The Institute and the Royal Marsden a DNA and family history register of the Royal Marsden patients for a wide range of cancers.Colorectal Cancer Susceptibility CORGI (ColORectal tumour Gene Identification) study. “Normal and tumour tissue have been obtained from a random subset of 1,000 patients entered into a trial of 10,000 colorectal cancer patients evaluating use of 5-FU. Using this resource we are exploring if tumour genotypes can predict prognosis or response to therapy.”Proteus Syndrome Juvenile Polyposis Peutz-Jeghers Syndrome Multiple Leiomyomatosis Neurofibromatosis (NF) type 1 Lung Cancer Susceptibility [GELCAPS consortium]” – http://www.icr.ac.uk/cancgen/molgen/mgteam.htm
  • The National Research Register (NRR) UK: “is a database of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom’s National Health Service (NHS. About 350 organisations (NHS Trusts, national and regional funding programmes, universities, charities) in England, Scotland and Wales contribute data which is updated every three months. The Register provides a reasonable record of projects that were ongoing from early 2000 onwards…” – http://www.nrr.nhs.uk/
  • Oxford Regional Prospective Study (ORPS) and UK Nephropathy Family Study (NFS): “The risk of serious diabetic complications has been much reduced by recent improvements in achieving good control of blood glucose in children with diabetes. However, a few children will still develop problems with their kidneys and eyes when they become adults. As well as being related to blood glucose levels, the risk of complications may be partly inherited. Some of the genes may determine the risk of developing complications. Small leaks of protein in the urine of children and adolescents with diabetes (microalbuminuria) may be the first marker of the later risk for complications. We plan to investigate the relationship between protein in the urine of children with diabetes and blood pressure, blood fats and urinary protein excretion in their parents. We will also study the genes in the parents and the children to see if they explain these relationships. The study has recruited 1,000 children who are being followed up for four years to see how they progress.” – http://www-gene.cimr.cam.ac.uk/ucdr/neph.shtml
  • Twin Research UK: “We provide a list of the vast majority of phenotypes that have been collected on at least 1,000 individuals in the Twins UK study” – http://www.twin-research.ac.uk/
  • UK GRID: Genetic Resource Investigating Diabetes: “The UK GRID Project was set up to collect blood samples from very large numbers of patients with type 1 diabetes, and in some cases, their family members, in order to conduct large-scale studies into the genetics of type 1 diabetes. For the purposes of the study, we have divided the United Kingdom into fifteen distinct regions. Each region has a “Lead Clinician(s)”, who helps recruit and coordinate the other centres in their area. These regional structures will also be used in the planning of the Children’s Diabetes Register. GRID encompasses two main studies: a collection of samples from 8,000 people, mostly children, with type 1 diabetes (the National DNA Collection); and 1,500 families, with a child with type 1 diabetes and followed for some time during the study for factors that might allow us to predict the possible future development of diabetic complications (the Oxford Regional Prospective Study, ORPS and the Nephropathy Family Study, NFS).” – http://www-gene.cimr.cam.ac.uk/ucdr/grid.shtml
  • Vesicoureteric Reflux (VUR) ASPs/nuclear families: “It is our aim to collect blood samples and data relating to disease, diagnosis, progression and treatment of VUR from 300 families – MOTHER, FATHER, INDEX CASE AND AFFECTED SIBLING(S). These families will be retrieved from the BAPN renal units and other interested physicians across the UK. To date (2005) we have identified 170 families, contacted150, replies from 140 and blood samples from 110.” – http://www.britishrenal.org/conferences/brs2004/Poster%20Abstracts/Pre%20Dial%202.pdf

United States of America

  • AGRE – autism genetic resource exchange: “The goal of AGRE is to facilitate more rapid progress in the identification of the genetic underpinnings of autism and Autism Spectrum Disorders by making this information available to the scientific community. This substantial collection, has now grown to almost 700 multiplex and simplex families.” – http://www.agre.org/index.cfm
  • Atherosclerosis Risk in Communities (ARIC) Ancillary Study of Susceptibility Genes for Diabetes, Obesity, and Hyperinsulinemia: “Included were 11,475 whites and 4,260 African-Americans aged 45-64 at baseline (1986-89), from four U.S. communities–Washington County, MD (Johns Hopkins); Forsyth County, NC (Bowman-Gray/University of North Carolina); Jackson, MI (University of Mississippi); and suburban Minneapolis, MN (University of Minnesota). Data collected at baseline included … <4 repeat visits up to 2004>. Diabetes risk substudy to identify associations between functional variants (if known) or estimated haplotypes in candidate susceptibility genes and the risk of type 2 diabetes in a community-based sample of approximately 9000 middle-aged adults from the ARIC cohort.” – http://www.jhsph.edu/cvdepi/Research_Projects/Research%20Projects%20Descriptions
  • Breast, ovarian and colon cancer: “North American family registries for breast/ovarian and colon cancer” – http://epi.grants.cancer.gov/CFR/
  • Clefts of the lip and palate “are common human birth defects of multifactorial etiology and with important surgical, medical, speech, behavioral and developmental implications. Currently, we are carrying out an expanded case ascertainment using both surveillance systems in the United States and overseas, particularly in the Philippines under the auspices of Operation Smile.” http://genetics.uiowa.edu/projects/projectDescriptions/MolEpiCLP.htm
  • ClinicalTrials.gov / US NIH listing of registered clinical trials: “ClinicalTrials.gov provides regularly updated information about federally and privately supported clinical research in human volunteers, observational as well as drug trials. ClinicalTrials.gov gives you information about a trial’s purpose, who may participate, locations, and phone numbers for more details. Trial protocol information is also given. Note that many trials now collect DNA. There is a search engine, a search on the word ‘genetic’ brings up >700 entries.” – http://www.clinicaltrials.gov/
  • Collaborative Study on the Genetics of Alcoholism (COGA) study: “The Collaborative Study on the Genetics of Alcoholism (COGA) study assessed 987 individuals from 105 multigenerational families selected through 23 female and 82 male adults in metropolitan inpatient and outpatient alcoholism treatment programs. Each of the 105 families contained at least three first-degree relatives with alcohol dependence. Like alcoholics in the general U.S. population, the study group was predominantly Caucasian and evidenced considerable comorbidity with other psychiatric diagnoses. COGA investigators now are analyzing results from a second scan in a similarly ascertained replication sample with 157 families and 1313 informative members.” – http://www.niaaa.nih.gov/ResearchInformation/ExtramuralResearch/SharedResources/projcoga.htm
  • Flint Men’s Health Study (African-Americans /prostate cancer): “The study began collecting data in 1996 and identified 817 eligible African-American men ages 40-79 to participate. The study subjects were recruited from Flint, Mich., an urban area north of Detroit. Of the eligible group, 369 participants underwent an interview, clinical exam and serum test. Researchers contacted the participants again in 2000 for further testing; 183 took part in the second wave.” – http://www.mydna.com/health/prostate_cancer/ethnicity/msr1pc.html
  • GALA – Genetics of Asthma in Latino Americans: “It is now well established that among U.S. residents of similar socio-economic status, there is greater asthma morbidity and mortality among Latino Americans and African Americans than among Caucasian Americans; and specifically, reported rates of asthma morbidity and mortality are higher among Puerto Rican Americans than among Mexican Americans. We will recruit Latino American asthmatic children (probands) and their biologic parents (n=2400) from California, New York, Mexico City and Puerto Rico during a 2 year period. Probands will undergo formal phenotypic characterization.” – http://pulmonary.ucsf.edu/research/gala.html
  • Genetics of Kidneys in Diabetes Study (GoKinD): “GoKinD has recruited over 2,700 participants including 243 case subjects with two parents (trios), 283 control-subject trios, 559 case-subject singletons, and 565 control-subject singletons. In all, this collection includes 802 individuals with both T1D and renal disease and 848 individuals with T1D and no renal disease. It will also include 1650 individuals with T1D and 526 T1D trios. Recruitment of new families for the study is closed as of November 2004. In the three and a half years of the recruitment phase the GoKinD study has screened more than 5500 participants by phone and in person.” – http://www.gokind.org/access/home.html
  • ISGS – Ischaemic Stroke Genetics Study (protocol): “All protocols for the Ischemic Stroke Genetic Study – this is a prospective, multicenter genetic association study in adults with recent first-ever ischemic stroke confirmed with computed tomography or magnetic resonance imaging. Patients are evaluated at academic medical centers in the United States and compared with sex- and age-matched controls. Stroke subtypes are determined by central blinded adjudication using standardized, validated mechanistic and syndromic classification systems. Immortalized cell lines are created” – http://www.biomedcentral.com/1471-2377/3/4
  • MS DNA bank – UCLA: “So far, Hauser has banked material from hundreds of families, totaling thousands of individuals, and including approximately 1,000 people with MS. Based on analyses of the first 180 families, Hauser’s team is focusing on six regions that seem to have the greatest likelihood of contributing to the risk of MS.” – http://www.nationalmssociety.org/pdf/research/ResearchHighlightsSummerFall02.pdf
  • The National Birth Defects Prevention Study Centralized Laboratory: “Over 5,000 specimens were received last year at CDC. Since its inception, the NBDPS Centralized Laboratory has received at least 6,000 buccal specimens, and 95.1 % of DNA samples have successfully passed the quality-control process. This high success rate will enhance the utility of this resource in investigations of genetic risk factors for birth defects. Slide information at www.mass.gov/dph/fch/birthdefects/mcbdrp_09_04.ppt” – http://www.cdc.gov/genomics/activities/ogdp/2004/eoipcoc.htm
  • Parkinson’s Disease Molecular Epidemiology (NIEHS funded): “The aim of this research is to discover genes which modify risk for Parkinson’s disease. The study includes 800 patients with Parkinson’s disease, and their estimated 1,222 available siblings. Common variations of at least 9 genes will be studied, including genes associated with personality, substance use, and anxiety and depression” – http://www.clinicaltrials.gov/ct/show/NCT00042107
  • Pharmacogenomics and Risk of Cardiovascular Disease: “The main objective of PARC is to both define and confirm the genetic contribution to the large inter-individual variability in the effects statin drugs on cardiovascular disease risk. The analyses have been based on measurements of lipoproteins and other cardiovascular risk markers in a cohort of 944 Caucasians and African-Americans who were treated with simvastatin 40 mg/day in a carefully supervised six-week trial. Linkage disequilibrium analysis of SNPs identified in a total of 78 genes was used to determine 891 tag sites that were genotyped in the first half of the cohort. In addition, we have completed pilot studies of pharmacogenetics of blood pressure response to ACE inhibitors in two study cohorts. In total, these studies will result in deposits in the PharmGKB database of nearly 800,000 individual genotypes as well as the measured phenotypes from both the statin and ACE inhibitor trials.” – http://www.pharmgkb.org/network/members/parc.jsp#team
  • Project SUGAR: “African American patients with diabetes and obesity, as well as their families, living on or near barrier islands along the SC coast (“Sea Islands”) are recruited through clinics, churches, community centers, and other health organizations serving these communities. The Sea Islanders are descendants of people transported from the rice-growing areas of West Africa who have inhabited the islands since the early 1700s. characterized by the highest degree of genetic homogeneity among African Americans and a very low degree of Caucasian admixture as well as large, stable multi-generation families, a diet that is uniformly high in fat content, and a common cultural identity and dialect (Gullah) corresponding to their West African origins. More than 425 families have been enrolled, and more than 1,200 family members have been fully phenotyped including >800 with Type 2 diabetes.” – http://research.musc.edu/bp/spec_sugar.html
  • Prostate Cancer Studies / National Cancer Institute USA: “Case-Control Study in Shanghai: 237 cancer cases, 206 patients with benign prostatic hyperplasia, and 471 healthy controls randomly selected from the population. Ghana Prostate Cancer Study. Accra. 500 cases. 1,000 controls. PSA, examination (+/-biopsy), questionnaire.Hormonal/biochemical markers. 1,400 cases and 1,400 controls within the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial for roles of insulin resistance and inflammation. NCI-ACS Collaborative Study, 1209 cases, 1209 controls. Case-control study within the Washington County CLUE Cohort Study.In 1974, over 8,000 male residents of Washington County, Maryland, donated a blood sample and completed a health questionnaire. IGF1 role. Prostate cancer risk following benign prostatic hyperplasia in Sweden and Denmark.86,626 Swedish BPH patients diagnosed during 1964-1983 and 86,683 Danish BPH patients diagnosed during 1977-1993” – http://dceg.cancer.gov/prost-cancer.html
  • Schizophrenia & Bipolar Disorder: “Extensive population and family collections for schizophrenia and bipolar disorder.” – http://www.hopkinsmedicine.org/epigen/

Copyright © 2007-2024.  Canadian Neighbor Pharmacy by Oege.org